WebApr 8, 2024 · The review titled “Current Main Topics in Multiple Myeloma” by Sonia Morè et al. discusses various topics on risk stratification, treatment, and management of Multiple Myeloma. Quite a few areas are covered relating to current developments of multiple myeloma, and it is very well written. It is believed that this article can be published ... WebAllogeneic hematopoietic stem cell transplantation (allo-HSCT) is the best treatment option for high-risk AML patients; however, it is not appropriate for every patient, especially elderly individuals. ... The emergence of immune therapy greatly improves the prognosis of lymphoma and myeloma patients and even substitutes for chemotherapy in B ...
A second‐generation CD38‐CAR‐T cell for the treatment of multiple myeloma
WebJun 7, 2024 · Novel immunotherapies, such as CAR T cell therapy (CAR) and bispecific T cell engagers (BiTE), are intensively targeting different surface antigens, such as BMCA, SLAMF7 (CS1), GPRC5D, FCRH5 or CD38. However, stem cell transplantation is still indispensable in transplant-eligible patients. WebSep 17, 2024 · B cell maturation antigen (BCMA) is a novel treatment target for multiple myeloma (MM) due to its highly selective expression in malignant plasma cells (PCs). Multiple BCMA-targeted therapeutics, including antibody-drug conjugates (ADC), chimeric antigen receptor (CAR)-T cells, and bispecific T cell …. B cell maturation antigen … hou to drcw c wan sion
B-cell maturation antigen (BCMA) in multiple myeloma: rationale …
WebOct 25, 2024 · On October 25, 2024, the Food and Drug Administration granted accelerated approval to teclistamab-cqyv (Tecvayli, Janssen Biotech, Inc.), the first bispecific B-cell maturation antigen... WebNov 5, 2024 · The B-Cell Maturation Antigen (BCMA) serves as a target for T cell directed therapy either by CAR-T or bispecific antibodies (BiAb's) in relapsed or refractory multiple myeloma patients. WebApr 11, 2024 · Multiple myeloma (MM) is an incurable cancer of the plasma cells. In the last twenty years, treatment strategies have evolved toward targeting MM cells—from the shotgun chemotherapy approach to the slightly more targeted approach of disrupting important MM molecular pathways to the immunotherapy approach that specifically … hou to find yellowstone on tv